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Health Care Value and Payment Innovations

Diagnosing Hope: The New Era of Alzheimer’s Disease Treatment Hinges on Innovations in Diagnostics

The approval of anti-amyloid drug therapies marks a new era in Alzheimer's care. Success depends on early screening and precise diagnosis of amyloid-related Alzheimer's, but this requires a shift towards early detection of a disease often diagnosed too late.

A new era of care for Alzheimer’s disease has begun with the approval of anti-amyloid drug therapies. Effective treatment utilizing the new therapies will hinge on early dementia screening and on accurate diagnosis of amyloid-related Alzheimer’s disease. Effective treatment of Alzheimer’s disease will ultimately require early detection and diagnosis, not only of amyloid plaques but also of multiple, complex drivers of Alzheimer’s disease progression among patients. Fortunately, innovations in diagnostics are creating new capabilities for “right test, right time, right patient” testing that should support the introduction of a broad range of therapies in the future. These innovations, however, will also compel a significant paradigm shift toward early detection and diagnosis of a disease that is rarely diagnosed at early stages today.

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Additional Authors

Lauren Bedel

Lauren Bedel, M.P.H.

Senior Health Policy and Program Associate, NEHI

Ashley Francis Policy Intern, NEHI

Ashley Francis

Policy Intern, NEHI

Barrett Laird  Policy Intern, NEHI

Barrett Laird, M.P.H.

Policy Intern, NEHI

Project Sponsors

NEHI wishes to thank its roundtable panelists and subject matter experts for their participation, advice, and counsel. They are:

  • Hannah Mamuszka, MS, Alva10
  • Joel Braunstein, MD, MBA, C2N Diagnostics
  • Elizabeth Somers, Eisai Inc.
  • Laura Cohen, JD & Adam Phipps, MBA, Eli Lilly & Company
  • Brian Carey, JD, Foley Hoag LLP
  • Hartmuth Kolb, Ph.D, Janssen/Johnson & Johnson
  • Linda K. McEvoy, Ph.D., Kaiser Permanente Washington Health Research Institute
  • Hampus Hillerstrom, MEcon, MBA, MSc, LuMind IDSC Foundation
  • Claire Levesque, MD, formerly Point32Health
  • Anil Nasta, MD & Cassandra Ricci, Roche Diagnostics
Tom Hubbard, M.P.P

Tom Hubbard, M.P.P

Senior Vice President of Policy Research, NEHI

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